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We believe that Gs-coupled GPCRs in intestinal L-cells, the main pathway for GLP-1 secretion, could serve as novel drug targets by acting as primary signals for GLP-1 secretion

(2016), the nutrient composition of baobab fruit pulp from three locations varied in terms of fat (ranging from 0.46 to 1.98 g/100 g), ash (ranging from 4.75 to 5.21 g/100 g), fiber (ranging from 5.91 to 9.65 g/100 g), protein (ranging from 3.23 to 3.53 g/100 g), and carbohydrate (ranging from 80.49 to 85.19 g/100 g)

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The 12-month trial design enables us to assess senolytic-associated changes before and after treatment during the 3-month active treatment phase, track the reappearance of senescent cells after their removal during the 9-month post-treatment period, and evaluate disease trajectory differences over a one-year period (Figure 3)

10.1016/j.beem.2012.05.002 75 PetrosilloG.MateraM.MoroN.RuggieroF